We will conduct a pilot test of using bone marrow derived cells to prevent the loss of kidney function. Individuals with diabetic kidney disease who have lost 50% or more of their kidney function but do not require dialysis will be eligible to participate.
Using mobile lab equipment, screening teams will travel to communities and test for CKD and its risk factors, including diabetes and high blood pressure. This information will be used to determine an individual’s risk of CKD, and each person will receive a treatment plan that is tailored to their risk.
AdDIT is studying an observational cohort of youth with type 1 diabetes along with a group of healthy age-matched subjects and longitudinally assessing both kidney function and cardiovascular function.
The AdDIT (Adolescent Diabetes Cardio-Renal Intervention Trial) and iCARE (Improving Renal Complications in Adolescents with Type 2 Diabetes through Research) studies are working together to identify the most important risk factors for early kidney disease in youth with diabetes.